SARS-CoV-2 spike-ferritin-nanoparticle adjuvanted with ALFQ induces long-lived plasma cells and cross-neutralizing antibodies

This study demonstrates the impact of adjuvant on the development of T follicular helper (Tfh) and B cells, and their influence on antibody responses in mice vaccinated with SARS-CoV-2-spike-ferritin-nanoparticle (SpFN) adjuvanted with either Army Liposome Formulation containing QS-21 (SpFN + ALFQ)...

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Detalles Bibliográficos
Autores principales: Shrivastava, Shikha, Carmen, Joshua M., Lu, Zhongyan, Basu, Shraddha, Sankhala, Rajeshwer S., Chen, Wei-Hung, Nguyen, Phuong, Chang, William C., King, Jocelyn, Corbitt, Courtney, Mayer, Sandra, Bolton, Jessica S., Anderson, Alexander, Swafford, Isabella, Terriquez, Guillermo D., Trinh, Hung V., Kim, Jiae, Jobe, Ousman, Paquin-Proulx, Dominic, Matyas, Gary, R., Gromowski, Gregory D., Currier, Jeffrey R., Bergmann-Leitner, Elke, Modjarrad, Kayvon, Michael, Nelson L., Joyce, M. Gordon, Malloy, Allison M. W., Rao, Mangala
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10024299/
https://www.ncbi.nlm.nih.gov/pubmed/36934088
http://dx.doi.org/10.1038/s41541-023-00638-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10024299/
https://www.ncbi.nlm.nih.gov/pubmed/36934088
http://dx.doi.org/10.1038/s41541-023-00638-6

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