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The Impact of Process and Formulation Parameters on the Fabrication of Efavirenz Nanosuspension to Improve Drug Solubility and Dissolution

BACKGROUND: Efavirenz nanosuspensions (EZ-NSs) were developed by the wet milling method as the most promising top-down nanosizing technique. Different process and formulation parameters were studied and optimized to produce appropriate EZ-NS in suitable conditions to enhance drug dissolution. METHOD...

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Detalles Bibliográficos
Autores principales: Rashed, Mahtab, Dadashzadeh, Simin, Bolourchian, Noushin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Brieflands 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10024318/
https://www.ncbi.nlm.nih.gov/pubmed/36942076
http://dx.doi.org/10.5812/ijpr-129409