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Computational and Experimental Evaluation of Linker Peptides and Thioredoxin Fusion Tag in CD20-rituximab Specific Interactions

BACKGROUND: Overexpression of CD20 protein on the surface of B cells in lymphoma can be targeted by several anti-CD20 molecules. The development of accessible interactive epitopes is more favorable than the full-length transmembrane CD20 in the affinity assessment of anti-CD20 monoclonal antibodies...

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Detalles Bibliográficos
Autores principales: Damough, Shadi, Alizadeh, Reyhaneh, Komijani, Samira, Shirin, Mahsa, Adeli, Ahmad, Mafakher, Ladan, Mahboudi, Fereidoun, Talebkhan Garoosi, Yeganeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Brieflands 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10024333/
https://www.ncbi.nlm.nih.gov/pubmed/36942068
http://dx.doi.org/10.5812/ijpr-134267