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Oscillatory shear stress modulates Notch-mediated endothelial mesenchymal plasticity in cerebral arteriovenous malformations

BACKGROUND: Cerebral arteriovenous malformations (cAVM) are a significant cause of intracranial hemorrhagic stroke and brain damage. The arteriovenous junctions in AVM nidus are known to have hemodynamic disturbances such as altered shear stress, which could lead to endothelial dysfunction. The mole...

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Detalles Bibliográficos
Autores principales: Karthika, C. L., Venugopal, Vani, Sreelakshmi, B. J., Krithika, S., Thomas, Jaya Mary, Abraham, Mathew, Kartha, C. C., Rajavelu, Arumugam, Sumi, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10024393/
https://www.ncbi.nlm.nih.gov/pubmed/36934253
http://dx.doi.org/10.1186/s11658-023-00436-x