Exosome-derived circCCAR1 promotes CD8 + T-cell dysfunction and anti-PD1 resistance in hepatocellular carcinoma

BACKGROUND: Circular RNAs (circRNAs) can be encapsulated into exosomes to participate in intercellular communication, affecting the malignant progression of a variety of tumors. Dysfunction of CD8 + T cells is the main factor in immune escape from hepatocellular carcinoma (HCC). Nevertheless, the ef...

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Detalles Bibliográficos
Autores principales: Hu, Zongqiang, Chen, Gang, Zhao, Yingpeng, Gao, Hongqiang, Li, Laibang, Yin, Yanfeng, Jiang, Jie, Wang, Li, Mang, Yuanyi, Gao, Yang, Zhang, Shengning, Ran, Jianghua, Li, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10024440/
https://www.ncbi.nlm.nih.gov/pubmed/36932387
http://dx.doi.org/10.1186/s12943-023-01759-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10024440/
https://www.ncbi.nlm.nih.gov/pubmed/36932387
http://dx.doi.org/10.1186/s12943-023-01759-1

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