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Downregulation of Lysosome-Associated Membrane Protein-2A Contributes to the Pathogenesis of COPD

BACKGROUND: Macroautophagy plays an important role in the pathogenesis of chronic obstructive pulmonary disease (COPD), but the role of chaperone-mediated autophagy (CMA) has not been investigated. We investigated if and how CMA is involved in the pathogenesis of COPD. METHODS: We measured the level...

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Detalles Bibliográficos
Autores principales: Jeong, Yun-Jeong, Lee, Kyoung-Hee, Woo, Jisu, Kim, Ji Yeon, Lee, Chang-Hoon, Yoo, Chul-Gyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10024500/
https://www.ncbi.nlm.nih.gov/pubmed/36942278
http://dx.doi.org/10.2147/COPD.S378386