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Common Variables That Influence Sepsis Mortality in Mice

INTRODUCTION: Sepsis is characterized by a dysregulated host immune response to infection, leading to organ dysfunction and a high risk of death. The cecal ligation and puncture (CLP) mouse model is commonly used to study sepsis, but animal mortality rates vary between different studies. Technical f...

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Detalles Bibliográficos
Autores principales: Garcia, Luiz F, Singh, Vishwajeet, Mireles, Blake, Dwivedi, Alok Kumar, Walker, Wendy E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10024505/
https://www.ncbi.nlm.nih.gov/pubmed/36941984
http://dx.doi.org/10.2147/JIR.S400115