Severity of Lung Function Impairment Drives Transcriptional Phenotypes of COPD and Relates to Immune and Metabolic Processes

PURPOSE: This study sought to characterize transcriptional phenotypes of COPD through unsupervised clustering of sputum gene expression profiles, and further investigate mechanisms underlying the characteristics of these clusters. PATIENTS AND METHODS: Induced sputum samples were collected from pati...

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Detalles Bibliográficos
Autores principales: Negewo, Netsanet A, Gibson, Peter G, Simpson, Jodie L, McDonald, Vanessa M, Baines, Katherine J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10024507/
https://www.ncbi.nlm.nih.gov/pubmed/36942279
http://dx.doi.org/10.2147/COPD.S388297

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10024507/
https://www.ncbi.nlm.nih.gov/pubmed/36942279
http://dx.doi.org/10.2147/COPD.S388297

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