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Severity of Lung Function Impairment Drives Transcriptional Phenotypes of COPD and Relates to Immune and Metabolic Processes

PURPOSE: This study sought to characterize transcriptional phenotypes of COPD through unsupervised clustering of sputum gene expression profiles, and further investigate mechanisms underlying the characteristics of these clusters. PATIENTS AND METHODS: Induced sputum samples were collected from pati...

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Detalles Bibliográficos
Autores principales:	Negewo, Netsanet A, Gibson, Peter G, Simpson, Jodie L, McDonald, Vanessa M, Baines, Katherine J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2023
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10024507/ https://www.ncbi.nlm.nih.gov/pubmed/36942279 http://dx.doi.org/10.2147/COPD.S388297

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