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Effects of C1-INH Treatment on Neurobehavioral Sequelae and Late Seizures After Traumatic Brain Injury in a Mouse Model of Controlled Cortical Impact

C1 human-derived C1 esterase inhibitor (C1-INH) is a U.S. Food and Drig Administration–approved drug with anti-inflammatory actions. In the present study, we investigated the therapeutic effects of C1-INH on acute and chronic neurobehavioral outcomes and on seizures in the chronic stage in a mouse t...

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Detalles Bibliográficos
Autores principales: Chen, Min, Tieng, Quang M., Du, Jiaxin, Edwards, Stephen R., Maskey, Dhiraj, Peshtenski, Emil, Reutens, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10024590/
https://www.ncbi.nlm.nih.gov/pubmed/36941878
http://dx.doi.org/10.1089/neur.2022.0011