Elamipretide mitigates ischemia-reperfusion injury in a swine model of hemorrhagic shock

ischemia-reperfusion injury (IRI) after hemorrhage is potentiated by aortic occlusion or resuscitative endovascular balloon occlusion of the aorta (REBOA). Given the central role of mitochondrial injury in shock, we hypothesized that Elamipretide, a peptide that protects mitochondria, would mitigate...

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Detalles Bibliográficos
Autores principales: Patel, N., Johnson, M. A., Vapniarsky, N., Van Brocklin, M. W., Williams, T. K., Youngquist, S. T., Ford, R., Ewer, N., Neff, L. P., Hoareau, G. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10024723/
https://www.ncbi.nlm.nih.gov/pubmed/36934127
http://dx.doi.org/10.1038/s41598-023-31374-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10024723/
https://www.ncbi.nlm.nih.gov/pubmed/36934127
http://dx.doi.org/10.1038/s41598-023-31374-5

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