Cargando…

Acute liver steatosis translationally controls the epigenetic regulator MIER1 to promote liver regeneration in a study with male mice

The early phase lipid accumulation is essential for liver regeneration. However, whether this acute lipid accumulation can serve as signals to direct liver regeneration rather than simply providing building blocks for cell proliferation remains unclear. Through in vivo CRISPR screening, we identify...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Yanhao, Chen, Lanlan, Wu, Xiaoshan, Zhao, Yongxu, Wang, Yuchen, Jiang, Dacheng, Liu, Xiaojian, Zhou, Tingting, Li, Shuang, Wei, Yuda, Liu, Yan, Hu, Cheng, Zhou, Ben, Qin, Jun, Ying, Hao, Ding, Qiurong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10024732/
https://www.ncbi.nlm.nih.gov/pubmed/36934083
http://dx.doi.org/10.1038/s41467-023-37247-9