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Acute liver steatosis translationally controls the epigenetic regulator MIER1 to promote liver regeneration in a study with male mice
The early phase lipid accumulation is essential for liver regeneration. However, whether this acute lipid accumulation can serve as signals to direct liver regeneration rather than simply providing building blocks for cell proliferation remains unclear. Through in vivo CRISPR screening, we identify...
Autores principales: | Chen, Yanhao, Chen, Lanlan, Wu, Xiaoshan, Zhao, Yongxu, Wang, Yuchen, Jiang, Dacheng, Liu, Xiaojian, Zhou, Tingting, Li, Shuang, Wei, Yuda, Liu, Yan, Hu, Cheng, Zhou, Ben, Qin, Jun, Ying, Hao, Ding, Qiurong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10024732/ https://www.ncbi.nlm.nih.gov/pubmed/36934083 http://dx.doi.org/10.1038/s41467-023-37247-9 |
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