DNMT3A low-expression is correlated to poor prognosis in childhood B-ALL and confers resistance to daunorubicin on leukemic cells

BACKGROUND: Little is known about DNMT3A expression and its prognostic significance in childhood B cell acute lymphoblastic leukemia (B-ALL). METHODS: We determined DNMT3A mRNA expression in 102 children with B-ALL. Correlations with relapse-free survival (RFS) and common clinical characteristics we...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Weijing, Liu, Shugang, Wang, Chanjuan, Cui, Lei, Zhao, Xiaoxi, Liu, Wei, Zhang, Ruidong, Li, Zhigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10024838/
https://www.ncbi.nlm.nih.gov/pubmed/36934225
http://dx.doi.org/10.1186/s12885-023-10724-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10024838/
https://www.ncbi.nlm.nih.gov/pubmed/36934225
http://dx.doi.org/10.1186/s12885-023-10724-6

Ejemplares similares