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Disulfide Bond-Based SN38 Prodrug Nanoassemblies with High Drug Loading and Reduction-Triggered Drug Release for Pancreatic Cancer Therapy

PURPOSE: Chemotherapy is a significant and effective therapeutic strategy that is frequently utilized in the treatment of cancer. Small molecular prodrug-based nanoassemblies (SMPDNAs) combine the benefits of both prodrugs and nanomedicine into a single nanoassembly with high drug loading, increased...

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Detalles Bibliográficos
Autores principales: Zhong, Zhi-Xin, Li, Xu-Zhao, Liu, Jin-Tao, Qin, Nan, Duan, Hong-Quan, Duan, Xiao-Chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10024910/
https://www.ncbi.nlm.nih.gov/pubmed/36945256
http://dx.doi.org/10.2147/IJN.S404848