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Elevated markers of DNA damage and senescence are associated with the progression of albuminuria and restrictive lung disease in patients with type 2 diabetes

BACKGROUND: This study was conducted to investigate the cascade involving DNA damage, senescence, and senescence-associated secretory phenotype (SASP) in experimental diabetes and in a four-year follow-up study in patients with pre-diabetes and type 2 diabetes. METHODS: Kidney, lung, and liver were...

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Detalles Bibliográficos
Autores principales: Varun, Kumar, Zoltan, Kender, Alba, Sulaj, Manuel, Blume, Elisabeth, Kliemank, Dimitrios, Tsilingiris, Jan B, Groener, Maik, Brune, Khurrum, Shahzad, Berend, Isermann, Stephen, Herzig, Thomas, Fleming, Julia, Szendroedi, Peter, Nawroth, Stefan, Kopf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10025008/
https://www.ncbi.nlm.nih.gov/pubmed/36934657
http://dx.doi.org/10.1016/j.ebiom.2023.104516