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Adenoviral vectored vaccination protects against Crimean-Congo Haemorrhagic Fever disease in a lethal challenge model

BACKGROUND: The tick-borne bunyavirus, Crimean-Congo Haemorrhagic Fever virus (CCHFV), can cause severe febrile illness in humans and has a wide geographic range that continues to expand due to tick migration. Currently, there are no licensed vaccines against CCHFV for widespread usage. METHODS: In...

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Detalles Bibliográficos
Autores principales: Saunders, Jack E., Gilbride, Ciaran, Dowall, Stuart, Morris, Susan, Ulaszewska, Marta, Spencer, Alexandra J., Rayner, Emma, Graham, Victoria A., Kennedy, Emma, Thomas, Kelly, Hewson, Roger, Gilbert, Sarah C., Belij-Rammerstorfer, Sandra, Lambe, Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10025009/
https://www.ncbi.nlm.nih.gov/pubmed/36933409
http://dx.doi.org/10.1016/j.ebiom.2023.104523