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SIRT3 improved peroxisomes-mitochondria interplay and prevented cardiac hypertrophy via preserving PEX5 expression

The present study identified a novel mechanism underlying the protective effect of Sirtuin 3 (SIRT3) against pathological cardiac hypertrophy, beyond its well-accepted role as a deacetylase in mitochondria. SIRT3 modulates the peroxisomes-mitochondria interplay by preserving the expression of peroxi...

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Detalles Bibliográficos
Autores principales: Wang, Minghui, Ding, Yanqing, Hu, Yuehuai, Li, Zeyu, Luo, Wenwei, Liu, Peiqing, Li, Zhuoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10025106/
https://www.ncbi.nlm.nih.gov/pubmed/36906951
http://dx.doi.org/10.1016/j.redox.2023.102652