Hydrogen sulfide donor AP123 restores endothelial nitric oxide-dependent vascular function in hyperglycemia via a CREB-dependent pathway

Diabetes is associated with severe vascular complications involving the impairment of endothelial nitric oxide synthase (eNOS) as well as cystathionine γ-lyase (CSE) activity. eNOS function is suppressed in hyperglycaemic conditions, resulting in reduced NO bioavailability, which is paralleled by re...

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Detalles Bibliográficos
Autores principales: Montanaro, Rosangela, Vellecco, Valentina, Torregrossa, Roberta, Casillo, Gian Marco, Manzo, Onorina Laura, Mitidieri, Emma, Bucci, Mariarosaria, Castaldo, Sigismondo, Sorrentino, Raffaella, Whiteman, Matthew, Smimmo, Martina, Carriero, Flavia, Terrazzano, Giuseppe, Cirino, Giuseppe, d’Emmanuele di Villa Bianca, Roberta, Brancaleone, Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10025109/
https://www.ncbi.nlm.nih.gov/pubmed/36913800
http://dx.doi.org/10.1016/j.redox.2023.102657

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10025109/
https://www.ncbi.nlm.nih.gov/pubmed/36913800
http://dx.doi.org/10.1016/j.redox.2023.102657

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