Cholesterol confers ferroptosis resistance onto myeloid-biased hematopoietic stem cells and prevents irradiation-induced myelosuppression

There is growing appreciation that hematopoietic alterations underpin the ubiquitous detrimental effects of metabolic disorders. The susceptibility of bone marrow (BM) hematopoiesis to perturbations of cholesterol metabolism is well documented, while the underlying cellular and molecular mechanisms...

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Detalles Bibliográficos
Autores principales: Liu, Chaonan, Liao, Weinian, Chen, Jun, Yu, Kuan, Wu, Yiding, Zhang, Shuzhen, Chen, Mo, Chen, Fang, Wang, Song, Cheng, Tianmin, Wang, Junping, Du, Changhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10025135/
https://www.ncbi.nlm.nih.gov/pubmed/36906952
http://dx.doi.org/10.1016/j.redox.2023.102661

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10025135/
https://www.ncbi.nlm.nih.gov/pubmed/36906952
http://dx.doi.org/10.1016/j.redox.2023.102661

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