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Sequential alterations in diffusion metrics as correlates of disease severity in amyotrophic lateral sclerosis

BACKGROUND AND OBJECTIVE: The neuropathology of amyotrophic lateral sclerosis (ALS) follows a regional distribution pattern in the brain with four stages. Using diffusion tensor imaging (DTI), this pattern can be translated into a tract-based staging scheme to assess cerebral progression in vivo. Th...

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Detalles Bibliográficos
Autores principales: Müller, Hans-Peter, Behler, Anna, Münch, Maximilian, Dorst, Johannes, Ludolph, Albert C., Kassubek, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10025190/
https://www.ncbi.nlm.nih.gov/pubmed/36763176
http://dx.doi.org/10.1007/s00415-023-11582-9