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Metabolic Switching of Cultured Mesenchymal Stem Cells Creates Super Mitochondria in Rescuing Ischemic Neurons

Transfer of healthy mitochondria from mesenchymal stem cells (MSCs) to ischemic neurons represents a potent stroke therapeutic. MSCs were grown under ambient conditions (nMSCs) or a metabolic switching paradigm by alternating galactose and glucose in medium (sMSCs) and then assayed for oxygen consum...

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Detalles Bibliográficos
Autores principales: Gorsky, Anna, Monsour, Molly, Nguyen, Hung, Castelli, Vanessa, Lee, Jea-Young, Borlongan, Cesar V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10025198/
https://www.ncbi.nlm.nih.gov/pubmed/35857254
http://dx.doi.org/10.1007/s12017-022-08720-3