Determination of in vitro hepatotoxic potencies of a series of perfluoroalkyl substances (PFASs) based on gene expression changes in HepaRG liver cells

Per- and polyfluoroalkyl substances (PFASs) are omnipresent and have been shown to induce a wide range of adverse health effects, including hepatotoxicity, developmental toxicity, and immunotoxicity. The aim of the present work was to assess whether human HepaRG liver cells can be used to obtain ins...

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Detalles Bibliográficos
Autores principales: Louisse, Jochem, Fragki, Styliani, Rijkers, Deborah, Janssen, Aafke, van Dijk, Bas, Leenders, Liz, Staats, Martijn, Bokkers, Bas, Zeilmaker, Marco, Piersma, Aldert, Luijten, Mirjam, Hoogenboom, Ron, Peijnenburg, Ad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Organ Toxicity and Mechanisms
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10025204/
https://www.ncbi.nlm.nih.gov/pubmed/36864359
http://dx.doi.org/10.1007/s00204-023-03450-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10025204/
https://www.ncbi.nlm.nih.gov/pubmed/36864359
http://dx.doi.org/10.1007/s00204-023-03450-2

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