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Inhibitory receptors for HLA class I as immune checkpoints for natural killer cell-mediated antibody-dependent cellular cytotoxicity in cancer immunotherapy

Natural killer (NK) cells mediate potent anti-tumor responses, which makes them attractive targets for immunotherapy. The anti-tumor response of endogenous- or allogeneic NK cells can be enhanced through clinically available monoclonal antibodies that mediate antibody-dependent cellular cytotoxicity...

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Detalles Bibliográficos
Autores principales: Beelen, Nicky A., Ehlers, Femke A. I., Bos, Gerard M. J., Wieten, Lotte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10025219/
https://www.ncbi.nlm.nih.gov/pubmed/36261539
http://dx.doi.org/10.1007/s00262-022-03299-x