Selective quantitative N-functionalization of unprotected α-amino acids using NHC-Ir(III) catalyst

Unnatural amino acids are valuable building blocks with numerous applications. Here, we present a quantitative technique for accessing mono-N-functionalized amino acids directly from unprotected substrates using alcohols as alkylating agents and an NHC-Ir(III) catalyst. We detail specific steps for...

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Detalles Bibliográficos
Autores principales: Saavedra, Beatriz, Bermejo-López, Aitor, Raeder, Majken, Martín-Matute, Belén
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10025274/
https://www.ncbi.nlm.nih.gov/pubmed/36920910
http://dx.doi.org/10.1016/j.xpro.2023.102147

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10025274/
https://www.ncbi.nlm.nih.gov/pubmed/36920910
http://dx.doi.org/10.1016/j.xpro.2023.102147

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