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Selective quantitative N-functionalization of unprotected α-amino acids using NHC-Ir(III) catalyst
Unnatural amino acids are valuable building blocks with numerous applications. Here, we present a quantitative technique for accessing mono-N-functionalized amino acids directly from unprotected substrates using alcohols as alkylating agents and an NHC-Ir(III) catalyst. We detail specific steps for...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10025274/ https://www.ncbi.nlm.nih.gov/pubmed/36920910 http://dx.doi.org/10.1016/j.xpro.2023.102147 |