Proteoliposomes reconstituted with human aquaporin-1 reveal novel single-ion-channel properties

Human aquaporin 1 (hAQP1) forms homotetrameric channels that facilitate fluxes of water and small solutes across cell membranes. In addition to water channel activity, hAQP1 displays non-selective monovalent cation-channel activity gated by intracellular cyclic GMP. Dual water and ion-channel activi...

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Detalles Bibliográficos
Autores principales: Henderson, Sam W., Nakayama, Yoshitaka, Whitelaw, Murray L., Bruning, John B., Anderson, Peter A., Tyerman, Stephen D., Ramesh, Sunita A., Martinac, Boris, Yool, Andrea J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10025285/
https://www.ncbi.nlm.nih.gov/pubmed/36949749
http://dx.doi.org/10.1016/j.bpr.2023.100100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10025285/
https://www.ncbi.nlm.nih.gov/pubmed/36949749
http://dx.doi.org/10.1016/j.bpr.2023.100100

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