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Gene-wide significant association analyses of DNMT1 genetic variants with Parkinson’s disease

Background: DNA methylation plays an important role in Parkinson’s disease (PD) pathogenesis. DNA methyltransferase 1 (DNMT1) is critical for maintaining DNA methylation in mammals. The link between DNMT1 polymorphisms and PD remains elusive. Methods: The DNMT1 gene contained a total of 28 single nu...

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Detalles Bibliográficos
Autores principales: Wang, Jian-Yong, Cui, Lei, Shi, Hong-Yi, Chen, Ling-Hao, Jin, Ren-Wei, Jiang, Xiao-Xia, Chen, Zhu-Ling, Zhu, Jian-Hong, Zhang, Xiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10025298/
https://www.ncbi.nlm.nih.gov/pubmed/36950137
http://dx.doi.org/10.3389/fgene.2023.1112388