Evaluation of therapeutic effects of tetramethylpyrazine nitrone in Alzheimer’s disease mouse model and proteomics analysis

The pathophysiology of Alzheimer’s disease (AD) is multifactorial with characteristic extracellular accumulation of amyloid-beta (Aβ) and intraneuronal aggregation of hyperphosphorylated tau in the brain. Development of disease-modifying treatment for AD has been challenging. Recent studies suggest...

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Detalles Bibliográficos
Autores principales: Zhou, Xinhua, Huang, Kaipeng, Wang, Yuqiang, Zhang, Zaijun, Liu, Yingying, Hou, Qinghua, Yang, Xifei, Hoi, Maggie Pui Man
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10025301/
https://www.ncbi.nlm.nih.gov/pubmed/36950017
http://dx.doi.org/10.3389/fphar.2023.1082602

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10025301/
https://www.ncbi.nlm.nih.gov/pubmed/36950017
http://dx.doi.org/10.3389/fphar.2023.1082602

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