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Comprehensive analysis of the prognosis, tumor microenvironment, and immunotherapy response of SDHs in colon adenocarcinoma

BACKGROUND: Succinate dehydrogenase (SDH), one of the key enzymes in the tricarboxylic acid cycle, is mainly found in the mitochondria. SDH consists of four subunits encoding SDHA, SDHB, SDHC, and SDHD. The biological function of SDH is significantly related to cancer progression. Colorectal cancer...

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Detalles Bibliográficos
Autores principales: Nan, Han, Guo, Pengkun, Fan, Jianing, Zeng, Wen, Hu, Chonghan, Zheng, Can, Pan, Bujian, Cao, Yu, Ge, Yiwen, Xue, Xiangyang, Li, Wenshu, Lin, Kezhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10025334/
https://www.ncbi.nlm.nih.gov/pubmed/36949947
http://dx.doi.org/10.3389/fimmu.2023.1093974