Construction and validation of chemoresistance-associated tumor- infiltrating exhausted-like CD8+ T cell signature in breast cancer: cr-TILCD8TSig

BACKGROUND: Accumulating evidence has revealed that CD8+ T cell exhaustion (Tex) results in worse immunotherapy outcomes. However, the molecular functions and mechanisms of action of Tex in chemoresistance needed to be elucidated. METHODS: The populations of tumor-infiltrating CD8+ T cells (TILCD8Ts...

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Detalles Bibliográficos
Autores principales: Cai, DQ., Cai, Diankui, Zou, Yiping, Chen, Xumeng, Jian, Zhixiang, Shi, Mude, Lin, Ye, Chen, Jueming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10025395/
https://www.ncbi.nlm.nih.gov/pubmed/36949939
http://dx.doi.org/10.3389/fimmu.2023.1120886

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10025395/
https://www.ncbi.nlm.nih.gov/pubmed/36949939
http://dx.doi.org/10.3389/fimmu.2023.1120886

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