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Protein interaction studies in human induced neurons indicate convergent biology underlying autism spectrum disorders

Autism spectrum disorders (ASDs) have been linked to genes with enriched expression in the brain, but it is unclear how these genes converge into cell-type-specific networks. We built a protein-protein interaction network for 13 ASD-associated genes in human excitatory neurons derived from induced p...

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Detalles Bibliográficos
Autores principales: Pintacuda, Greta, Hsu, Yu-Han H., Tsafou, Kalliopi, Li, Ka Wan, Martín, Jacqueline M., Riseman, Jackson, Biagini, Julia C., Ching, Joshua K.T., Mena, Daya, Gonzalez-Lozano, Miguel A., Egri, Shawn B., Jaffe, Jake, Smit, August B., Fornelos, Nadine, Eggan, Kevin C., Lage, Kasper
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10025425/
https://www.ncbi.nlm.nih.gov/pubmed/36950384
http://dx.doi.org/10.1016/j.xgen.2022.100250