Conditioning on parental mating types can reduce necessary assumptions for Mendelian randomization

Mendelian randomization (MR) has become a common tool used in epidemiological studies. However, when confounding variables are correlated with the instrumental variable (in this case, a genetic/variant/marker), the estimation can remain biased even with MR. We propose conditioning on parental mating...

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Detalles Bibliográficos
Autores principales: Ejima, Keisuke, Liu, Nianjun, Mestre, Luis Miguel, de los Campos, Gustavo, Allison, David B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10025466/
https://www.ncbi.nlm.nih.gov/pubmed/36950138
http://dx.doi.org/10.3389/fgene.2023.1014014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10025466/
https://www.ncbi.nlm.nih.gov/pubmed/36950138
http://dx.doi.org/10.3389/fgene.2023.1014014

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