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Conditioning on parental mating types can reduce necessary assumptions for Mendelian randomization
Mendelian randomization (MR) has become a common tool used in epidemiological studies. However, when confounding variables are correlated with the instrumental variable (in this case, a genetic/variant/marker), the estimation can remain biased even with MR. We propose conditioning on parental mating...
Autores principales: | Ejima, Keisuke, Liu, Nianjun, Mestre, Luis Miguel, de los Campos, Gustavo, Allison, David B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10025466/ https://www.ncbi.nlm.nih.gov/pubmed/36950138 http://dx.doi.org/10.3389/fgene.2023.1014014 |
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