Niclosamide does not modulate airway epithelial function through blocking of the calcium activated chloride channel, TMEM16A

Niclosamide and benzbromarone have been described as inhibitors of the calcium activated chloride channel, TMEM16A, and on this basis have been considered and tested as clinical candidates for the treatment of airway diseases. However, both compounds have previously demonstrated activity on a range...

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Detalles Bibliográficos
Autores principales: Danahay, Henry, Lilley, Sarah, Adley, Kathryn, Charlton, Holly, Fox, Roy, Gosling, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10025480/
https://www.ncbi.nlm.nih.gov/pubmed/36950016
http://dx.doi.org/10.3389/fphar.2023.1142342

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10025480/
https://www.ncbi.nlm.nih.gov/pubmed/36950016
http://dx.doi.org/10.3389/fphar.2023.1142342

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