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Niclosamide does not modulate airway epithelial function through blocking of the calcium activated chloride channel, TMEM16A
Niclosamide and benzbromarone have been described as inhibitors of the calcium activated chloride channel, TMEM16A, and on this basis have been considered and tested as clinical candidates for the treatment of airway diseases. However, both compounds have previously demonstrated activity on a range...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10025480/ https://www.ncbi.nlm.nih.gov/pubmed/36950016 http://dx.doi.org/10.3389/fphar.2023.1142342 |