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Nitric Oxide Derived from Cytoglobin-Deficient Hepatic Stellate Cells Causes Suppression of Cytochrome c Oxidase Activity in Hepatocytes

AIMS: Cell–cell interactions between hepatocytes (Hep) and other liver cells are key to maintaining liver homeostasis. Cytoglobin (CYGB), expressed exclusively by hepatic stellate cells (HSC), is essential in mitigating mitochondrial oxidative stress. CYGB absence causes Hep dysfunction and evokes h...

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Detalles Bibliográficos
Autores principales: Okina, Yoshinori, Sato-Matsubara, Misako, Kido, Yasutoshi, Urushima, Hayato, Daikoku, Atsuko, Kadono, Chiho, Nakagama, Yu, Nitahara, Yuko, Hoang, Truong Huu, Thuy, Le Thi Thanh, Matsubara, Tsutomu, Ohtani, Naoko, Ikeda, Kazuo, Yoshizato, Katsutoshi, Kawada, Norifumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10025843/
https://www.ncbi.nlm.nih.gov/pubmed/36112670
http://dx.doi.org/10.1089/ars.2021.0279