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Restricting genomic actions of innate immune mediators on fetal hematopoietic progenitor cells

Innate immune signaling protects against pathogens, controls hematopoietic development, and functions in oncogenesis, yet the relationship between these mechanisms is undefined. Downregulating the GATA2 transcription factor in fetal hematopoietic progenitor cells upregulates genes encoding innate im...

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Detalles Bibliográficos
Autores principales: Tran, Vu L., Liu, Peng, Katsumura, Koichi R., Kim, Erin, Schoff, Bjorn M., Johnson, Kirby D., Bresnick, Emery H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10025987/
https://www.ncbi.nlm.nih.gov/pubmed/36950124
http://dx.doi.org/10.1016/j.isci.2023.106297