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Restricting genomic actions of innate immune mediators on fetal hematopoietic progenitor cells
Innate immune signaling protects against pathogens, controls hematopoietic development, and functions in oncogenesis, yet the relationship between these mechanisms is undefined. Downregulating the GATA2 transcription factor in fetal hematopoietic progenitor cells upregulates genes encoding innate im...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10025987/ https://www.ncbi.nlm.nih.gov/pubmed/36950124 http://dx.doi.org/10.1016/j.isci.2023.106297 |