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Single-cell RNA sequencing reveals maturation trajectory in human pluripotent stem cell-derived cardiomyocytes in engineered tissues

Cardiac in vitro models have become increasingly obtainable and affordable with the optimization of human pluripotent stem cell-derived cardiomyocyte (hPSC-CM) differentiation. However, these CMs are immature compared to their in vivo counterparts. Here we study the cellular phenotype of hPSC-CMs by...

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Detalles Bibliográficos
Autores principales: Cheng, Shangli, Brenière-Letuffe, David, Ahola, Virpi, Wong, Andy O.T., Keung, Hoi Yee, Gurung, Bimal, Zheng, Zongli, Costa, Kevin D., Lieu, Deborah K., Keung, Wendy, Li, Ronald A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10025988/
https://www.ncbi.nlm.nih.gov/pubmed/36950112
http://dx.doi.org/10.1016/j.isci.2023.106302