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Single-cell RNA sequencing reveals maturation trajectory in human pluripotent stem cell-derived cardiomyocytes in engineered tissues
Cardiac in vitro models have become increasingly obtainable and affordable with the optimization of human pluripotent stem cell-derived cardiomyocyte (hPSC-CM) differentiation. However, these CMs are immature compared to their in vivo counterparts. Here we study the cellular phenotype of hPSC-CMs by...
Autores principales: | Cheng, Shangli, Brenière-Letuffe, David, Ahola, Virpi, Wong, Andy O.T., Keung, Hoi Yee, Gurung, Bimal, Zheng, Zongli, Costa, Kevin D., Lieu, Deborah K., Keung, Wendy, Li, Ronald A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10025988/ https://www.ncbi.nlm.nih.gov/pubmed/36950112 http://dx.doi.org/10.1016/j.isci.2023.106302 |
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