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Isolation of slow-cycling cancer cells from lung patient-derived xenograft using carboxyfluorescein-succinimidyl ester retention-mediated cell sorting

The slow-cycling subpopulation plays an important role in anticancer drug resistance and tumor recurrence. Here, we describe a clinically relevant patient-derived xenograft model and a carboxyfluorescein succinimidyl ester dye that is diluted in a cell proliferation-dependent manner. We detail steps...

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Detalles Bibliográficos
Autores principales: Cho, Jaebeom, Min, Hye-Young, Lee, Ho-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10026031/
https://www.ncbi.nlm.nih.gov/pubmed/36924504
http://dx.doi.org/10.1016/j.xpro.2023.102167