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A protocol for capturing RNA-sensing innate immune receptors in multiple conformations by single-particle cryo-EM

Capturing different conformations of receptor proteins that are complexed with ligands by single-particle cryo-EM facilitates our understanding toward the mechanisms of ligand recognition and receptor activation cascades. Here, we present a protocol for capturing RNA-sensing innate immune receptors,...

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Detalles Bibliográficos
Autores principales: Wang, Wenshuai, Fedorova, Olga, Pyle, Anna Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10026036/
https://www.ncbi.nlm.nih.gov/pubmed/36920909
http://dx.doi.org/10.1016/j.xpro.2023.102166