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A protocol for capturing RNA-sensing innate immune receptors in multiple conformations by single-particle cryo-EM
Capturing different conformations of receptor proteins that are complexed with ligands by single-particle cryo-EM facilitates our understanding toward the mechanisms of ligand recognition and receptor activation cascades. Here, we present a protocol for capturing RNA-sensing innate immune receptors,...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10026036/ https://www.ncbi.nlm.nih.gov/pubmed/36920909 http://dx.doi.org/10.1016/j.xpro.2023.102166 |