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Pharmacogenetics of ABCB1 , CDA , DCK , GSTT1 , GSTM1 and outcomes in a cohort of pediatric acute myeloid leukemia patients from Colombia

BACKGROUND AND AIM: Different studies have shown pharmacogenetic variants related to drug toxicity in acute myeloid leukemia (AML) patients. Our aim was to identify the association between ABCB1, CDA, DCK, GSTT1, and GSTM1 variants with clinical outcomes and toxicity in pediatric patients with AML....

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Detalles Bibliográficos
Autores principales: Yunis, Luz K., Linares‐Ballesteros, Adriana, Aponte, Nelson, Barros, Gisela, García, Johnny, Niño, Laura, Uribe, Gloria, Quintero, Edna, Yunis, Juan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10026301/
https://www.ncbi.nlm.nih.gov/pubmed/36316809
http://dx.doi.org/10.1002/cnr2.1744