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Dexmedetomidine attenuates postoperative spatial memory impairment after surgery by reducing cytochrome C

BACKGROUND: Anesthesia and surgery can induce perioperative neurocognitive disorders (PND). Mitochondrial dysfunction has been proposed to be one of the earliest triggering events in surgery-induced neuronal damage. Dexmedetomidine has been demonstrated to attenuate the impairment of cognition in ag...

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Detalles Bibliográficos
Autores principales: Sun, Lina, Niu, Kun, Guo, Jian, Tu, Jingru, Ma, Baofeng, An, Jianxiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10026454/
https://www.ncbi.nlm.nih.gov/pubmed/36941579
http://dx.doi.org/10.1186/s12871-023-02035-x