IBIS: identify biomarker-based subgroups with a Bayesian enrichment design for targeted combination therapy

BACKGROUND: Combination therapies directed at multiple targets have potentially improved treatment effects for cancer patients. Compared to monotherapy, targeted combination therapy leads to an increasing number of subgroups and complicated biomarker-based efficacy profiles, making it more difficult...

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Detalles Bibliográficos
Autores principales: Chen, Xin, Zhang, Jingyi, Jiang, Liyun, Yan, Fangrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10026491/
https://www.ncbi.nlm.nih.gov/pubmed/36941537
http://dx.doi.org/10.1186/s12874-023-01877-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10026491/
https://www.ncbi.nlm.nih.gov/pubmed/36941537
http://dx.doi.org/10.1186/s12874-023-01877-w

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