Cargando…
IBIS: identify biomarker-based subgroups with a Bayesian enrichment design for targeted combination therapy
BACKGROUND: Combination therapies directed at multiple targets have potentially improved treatment effects for cancer patients. Compared to monotherapy, targeted combination therapy leads to an increasing number of subgroups and complicated biomarker-based efficacy profiles, making it more difficult...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10026491/ https://www.ncbi.nlm.nih.gov/pubmed/36941537 http://dx.doi.org/10.1186/s12874-023-01877-w |