Population Pharmacokinetic Modeling and Exposure‐Response Analysis for Aripiprazole Once Monthly in Subjects With Schizophrenia

An intramuscular formulation of aripiprazole monohydrate dosed once monthly (AOM) was developed to address nonadherence with the approved oral tablets. A 3‐compartment linear population pharmacokinetic model for oral and AOM doses was developed; relative bioavailability was estimated for AOM relativ...

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Detalles Bibliográficos
Autores principales: Wang, Xiaofeng, Raoufinia, Arash, Bihorel, Sébastien, Passarell, Julie, Mallikaarjun, Suresh, Phillips, Luann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10026531/
https://www.ncbi.nlm.nih.gov/pubmed/34979059
http://dx.doi.org/10.1002/cpdd.1022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10026531/
https://www.ncbi.nlm.nih.gov/pubmed/34979059
http://dx.doi.org/10.1002/cpdd.1022

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