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Population Pharmacokinetic Modeling and Exposure‐Response Analysis for Aripiprazole Once Monthly in Subjects With Schizophrenia
An intramuscular formulation of aripiprazole monohydrate dosed once monthly (AOM) was developed to address nonadherence with the approved oral tablets. A 3‐compartment linear population pharmacokinetic model for oral and AOM doses was developed; relative bioavailability was estimated for AOM relativ...
Autores principales: | Wang, Xiaofeng, Raoufinia, Arash, Bihorel, Sébastien, Passarell, Julie, Mallikaarjun, Suresh, Phillips, Luann |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10026531/ https://www.ncbi.nlm.nih.gov/pubmed/34979059 http://dx.doi.org/10.1002/cpdd.1022 |
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