Memantine has a nicotinic neuroprotective pathway in acute hippocampal slices after an NMDA insult

Memantine is a non-competitive antagonist with a moderate affinity to the N-methyl-D-Aspartate (NMDA) receptor. The present study assessed memantine’s neuroprotective activity using electrophysiology of ex-vivo hippocampal slices. Interestingly, a nicotinic component was necessary for memantine’s ne...

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Detalles Bibliográficos
Autores principales: Ferrer-Acosta, Yancy, Rodriguez-Massó, Sergio, Pérez, Dinely, Eterovic, Vesna A., Ferchmin, P.A., Martins, Antonio Henrique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10026604/
https://www.ncbi.nlm.nih.gov/pubmed/35944748
http://dx.doi.org/10.1016/j.tiv.2022.105453

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10026604/
https://www.ncbi.nlm.nih.gov/pubmed/35944748
http://dx.doi.org/10.1016/j.tiv.2022.105453

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