Dimerized fusion inhibitor peptides targeting the HR1–HR2 interaction of SARS-CoV-2

Membrane fusion is a critical and indispensable step in the replication cycles of viruses such as SARS-CoV-2 and human immunodeficiency virus type-1 (HIV-1). In this step, a trimer of the heptad repeat 1 (HR1) region interacts with the three HR2 regions and forms a 6-helix bundle (6-HB) structure to...

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Detalles Bibliográficos
Autores principales: Tsuji, Kohei, Baffour-Awuah Owusu, Kofi, Miura, Yutaro, Ishii, Takahiro, Shinohara, Kouki, Kobayakawa, Takuya, Emi, Akino, Nakano, Takashi, Suzuki, Youichi, Tamamura, Hirokazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10026625/
https://www.ncbi.nlm.nih.gov/pubmed/36950081
http://dx.doi.org/10.1039/d2ra07356k

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10026625/
https://www.ncbi.nlm.nih.gov/pubmed/36950081
http://dx.doi.org/10.1039/d2ra07356k

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